Chun Yuyi's greatest contribution to medicine was the creation of the "Clinic Book". As time went by, Chun Yuyi saw more and more patients. Many of the patients he had seen in the past came to him again when they encountered illnesses. He could no longer remember the diagnosis and prescriptions he had given before. . There are also some difficult diseases that have been treated in the past, but the prescriptions at that time were not retained, and now they have to start again. In this way, similar and identical work is often repeated, which results in half the result with half the effort. More importantly, it is not conducive to accumulating and summarizing experience. How to solve this problem? Chunyu Yi then began to record the patient's condition at any time during diagnosis and save it. From then on, all the patients he treated had medical records, which included the patient's name, occupation, residence, disease name, pulse, cause of disease, treatment, medication, efficacy, etc. He bound these medical records into a book and named it "Clinical Book". Twenty-five of these medical records were recorded in "Historical Records", making them the earliest medical records recorded in literature in my country. Its style was the origin of later medical records. Chunyu Yi's second greatest contribution to medicine was the development of Bian Que's medical theory. For example, in pulse diagnosis, Chunyu Yi defined various pulse conditions, and could diagnose the source of disease, lesions, disease transformation and prognosis based on pulse conditions. According to the "Pulse Method" quoted by Chun Yuyi, the concepts of pulse conditions proposed include length, string, harmony, generation, number, urgency, sinking, floating, etc. Many of them were adopted by later generations of pulse studies. Chunyu Yi has also formed a clear understanding of the distribution locations of meridians in the human body. When diagnosing patients, pulse diagnosis can be carried out based on the meridian theory, and the cause, condition and prognosis can be analyzed using this theory. Chunyu Yi's third greatest contribution to medicine was to change the way medical skills are taught. In ancient times, the dissemination of medical skills was a very mysterious way of single transmission, and disciples could not be accepted openly. This was not conducive to the spread of medical skills. Chunyu Yi did not care about personal gains and losses, and dared to break away from traditional customs. He turned the original very mysterious medical communication method into an open teaching method, which avoided the loss of medical skills and was conducive to the expansion of the medical team. Chun Yuyi taught medical skills to Song Yi, Gao Qi, Wang Yu, Feng Xin, Du Xin, and Tang An successively. It can be said that he was full of students and brought out a large number of outstanding doctors in Linzi, Zichuan, and Jibei areas at that time. A Qipai medical group has begun to take shape.