Stroke is a sudden disorder of cerebral blood circulation, also known as cerebrovascular accident. Let's take a closer look.
cellular transplantation
The onset of
Stroke is a sudden disorder of cerebral blood circulation, also known as cerebrovascular accident. Let's take a closer look.
cellular transplantation
The onset of stroke patients causes necrosis of nerve cells and tissues, thus causing various hemiplegic symptoms of patients. Human nerve cells are non-renewable. Stem cells are magical cells that can be regenerated. Transplanted stem cells can identify themselves and migrate to damaged nerve sites, and replace dead or damaged nerve cells in vivo by cell replacement to repair damaged neural networks. Transplanted cells can differentiate a large number of neurotrophic factors and activate these nerve cells, thus improving the nervous function of the body.
After suffering from a stroke, some central nerve cells are necrotic, which makes the brain, spinal cord and other nerve injuries and lesions always cause lifelong disability of patients. By extracting, separating and purifying the stem cells, they are injected into the damaged parts of the brain, so that the stem cells can play a therapeutic role in the regeneration and repair of damaged tissues and cells, reduce the apoptosis and necrosis of host nerve cells, restore the functions of damaged cells, and differentiate into a large number of functional cells to participate in the three-dimensional reconstruction of the brain and restore the signal transduction pathway. Achieve the purpose of treating apoplexy.
1, check the patient's condition and see if it is in line with stem cell therapy.
2. Select suitable stem cells and isolate and culture them.
3. Stem cell input. The main methods of stem cell infusion are intravenous infusion and puncture from lumbar cistern, once a week, 3 times in total.
4. Postoperative monitoring and observation of adverse reactions. Body temperature, blood pressure, respiration and other vital signs were monitored within 8 hours to 5 days after autotransplantation.
5. Postoperative rehabilitation training. Patients began to take functional exercise or hyperbaric oxygen therapy after operation 1 week for 3 courses.
6. Observe the treatment results. After two months of treatment, the symptoms of sequelae were improved, and some patients showed obvious improvement within one month. For example, patients with dysphagia can eat liquid; Improve intelligence; Muscle strength is improved; Patients can also walk by themselves without crutches.
Ultrasonic thrombolysis
1990-2003 American, Japanese and German societies reported the experimental study of 7 14 ultrasonic thrombolysis. Conclusion Ultrasound with certain power and frequency can directly dissolve thrombus and increase the activity of fibrinolytic drugs. Professor Lang Hongzhi, a domestic scholar, began to study transcranial ultrasound in the treatment of cerebrovascular diseases internationally from the 1970s. Through a large number of animal experiments, he proposed the safe dose of transcranial ultrasound for the first time in the world. Transcranial ultrasound thrombolysis is mainly used for thrombolytic therapy in the early stage of cerebral infarction. It can be used alone or at the same time with urokinase to improve the effect of thrombolytic therapy and reduce bleeding complications. In the convalescence and rehabilitation of stroke, this therapy can improve cerebral microcirculation, promote the establishment of lateral fat circulation, and accelerate the recovery of limb function and language disorder. In the early stage of cerebral infarction, such as cerebral arteriosclerosis, cerebrovascular stenosis, abnormal MRA or TCD and TIA attack, this treatment can eliminate atherosclerotic plaque, dilate cerebral vessels, reduce or disappear TIA attack and prevent the occurrence of cerebral infarction.
Chinese traditional treatment
costa
1, wind-phlegm entering collaterals syndrome
Ruthless skin, numbness of hands and feet, sudden mouth and eyes askew, unfavorable language, drooling, weakness of tongue, even hemiplegia, or symptoms such as hand and foot contracture and joint pain, thin and white tongue coating and floating pulse.
Summary of syndrome mechanism: pulse deficiency, wind-phlegm deficiency, qi and blood obstruction.
Treatment: expelling wind, resolving phlegm and dredging collaterals.
Representative: real square white ball addition and subtraction. This recipe can eliminate phlegm and dredge collaterals, and can be used to treat wind-phlegm entering the guest meridian, with symptoms such as mouth-eye deviation, strong tongue, paralysis of hands and feet, etc.
Commonly used drugs: Pinellia ternata, Rhizoma Arisaematis and Rhizoma Typhonii for expelling wind and resolving phlegm; Gastrodia elata and Scorpio extinguish wind and dredge collaterals; Radix Angelicae Sinensis, Radix Paeoniae Alba, Caulis Spatholobi and Herba Siegesbeckiae nourish blood and dispel wind.
If the language is unclear, add calamus and polygala tenuifolia to resolve phlegm and begin to understand; For patients with phlegm and blood stasis, purple tongue with ecchymosis and thready pulse, Radix Salviae Miltiorrhizae, Semen Persicae, Carthami Flos and Radix Paeoniae Alba can be added to promote blood circulation and remove blood stasis.
2. Syndrome of wind-yang imbalance
Usually dizziness, headache, tinnitus, sudden mouth and eyes? Strong tongue, or heavy stagnation of hands and feet, even paralysis of cattle, red tongue with yellow fur and thin pulse.
Summary of syndrome mechanism: hyperactivity of liver fire, hyperactivity of yang causing wind, and crossing of collaterals.
Treatment: calming the liver and suppressing yang, promoting blood circulation and dredging collaterals.
Representative: Tianma Gouteng Drink. This prescription is used for calming the liver, calming the wind and relieving latent heat, and is used for hyperactivity of yang, wind-induced dizziness, numbness of limbs, etc.
Commonly used drugs for stroke: Gastrodia elata and Uncaria rhynchophylla; Mother-of-pearl and concha Haliotidis inhibit liver yang; Mulberry leaves and chrysanthemums clear away liver and heat; Huangling. Shan Zhi clears liver and purges fire; Achyranthes bidentata promotes blood circulation and removes blood stasis, which reduces qi and blood.
Chen Danxing and Yujin are added for those with phlegm, chest tightness, nausea and greasy fur; For patients with severe headache, antelope horn and Prunella vulgaris are added to clear liver and calm wind; Heavy depression of legs and feet, plus Eucommia ulmoides, parasitic tonic liver and kidney.
3. Yin deficiency and wind-driven syndrome
Usually, dizziness, tinnitus, backache, sudden mouth-eye deviation, speech disorder, finger movement, even hemiplegia, red tongue, greasy fur and rapid pulse occur.
Summary of syndrome mechanism: yin deficiency of liver and kidney, wind and yang moving inward, wind and phlegm blocking collaterals.
Treatment: nourishing yin and suppressing yang, calming wind and dredging collaterals.
Representative: Modified Zhengan Xifeng Decoction. This prescription can not only tonify the yin of liver and kidney, but also extinguish wind and subdue yang, and is used for dizziness, headache, strong tongue and limb tremor.
Commonly used drugs: Radix Paeoniae Alba, Radix Asparagi, Radix Scrophulariae and Fructus Lycii nourish yin, soften liver and calm wind; Os Draconis, Concha Ostreae, Carapax et Plastrum Testudinis and ochre are used to suppress liver and yang; Achyranthes bidentata and Angelica sinensis promote blood circulation to remove blood stasis and lead blood downward; Gastrodia elata, Uncaria rhynchophylla, calming the liver and calming the wind.
Phlegm heat is heavy, fur is yellow and greasy, and pathogenic factors are widespread. Adding Danxing, Julie, and Bulbus Fritillariae Cirrhosae for clearing away heat and resolving phlegm; Yin deficiency and hyperactivity of yang, hyperactivity of liver fire, restlessness and heat in the heart, add Gardenia and Scutellaria to clear away heat.
internal organs
1, closed card
The main symptoms of amenorrhea are sudden coma, unconsciousness, clenched teeth, unable to open his mouth, clenched fists with both hands, closed defecation and severe limb spasm.
1 Phlegm-heat Syndrome of Fu-organs
It is called headache, dizziness, irritability, sudden onset, hemiplegia, crooked tongue, weak or silent tongue, unclear or delirious mind, tense limbs, excessive and sticky phlegm, accompanied by abdominal distension, constipation, dark red tongue, or petechiae, yellow and greasy fur, and slippery or astringent pulse.
Summary of syndrome mechanism: phlegm-heat blocking, wind-phlegm disturbing, fu-organs and qi blocking. Treatment: clearing fu-organs and clearing heat, calming wind and resolving phlegm.
Representative: Ren Tao Chengqi Decoction. This recipe has the effects of clearing away heat from fu-organs, reducing qi and blood, and can be used to treat the internal heat of fu-organs, abdominal distension and constipation, which can be used for the syndrome of phlegm-heat in fu-organs in acute stage of stroke.
Commonly used drugs: peach kernel, rhubarb, mirabilite, immature bitter orange, clearing heat, cooling blood and removing blood stasis; Chen Danxing, Scutellaria baicalensis Georgi and Trichosanthes kirilowii have the effects of clearing away heat and resolving phlegm, while peach kernel, red peony root and peony bark have the effects of cooling blood and removing blood stasis. Achyranthes bidentata leads qi and blood downward.
For patients with severe headache and dizziness, Uncaria rhynchophylla, Chrysanthemum and Mother of Pearl are added to calm the liver and reduce adverse reactions. Irritability, staying up late, adding Radix Rehmanniae, Radix Adenophorae and Caulis Polygoni Multiflori to nourish yin and soothe the nerves.
Syndrome of phlegm-fire and blood stasis
In addition to the above symptoms, there are red face and fever, bad breath, irritability, yellow greasy fur, slippery pulse and so on.
Summary of syndrome mechanism: hyperactivity of liver yang, hyperactivity of yang wind, inflammation of phlegm-fire, upwelling of qi and blood, ignorance.
Treatment: calming wind and clearing fire, resolving phlegm and inducing resuscitation.
Representative: antelope Uncaria soup. This recipe has the functions of cooling liver, calming wind, clearing away heat and resolving phlegm, nourishing yin and relaxing muscles and tendons, and is used for the disorder of wind and yang.
Those who suffer from dizziness, spasm and convulsion due to ignorance can also take Zhibaodan or Angong Niuhuang Pill to clear their heart and begin to understand. Can also use Xingnaojing or Qingkailing injection intravenous drip.
Commonly used drugs: antelope horn or horn, Uncaria rhynchophylla, mother-of-pearl, concha Haliotidis to calm the liver and calm the wind; Bile star, bamboo juice, Pinellia ternata, concretio silicea bambusae and coptis chinensis are used for clearing away heat and resolving phlegm; Acorus calamus and Radix Curcumae resolve phlegm and begin to understand.
If the phlegm is blocked in the airway and the sputum in the throat rumbles, you can take bamboo juice and monkey jujube powder to eliminate phlegm and relieve asthma; Strong liver fire: red face and eyes, strong pulse. Gentiana macrophylla, Gardenia, Prunella vulgaris, ochre, magnet and other liver-clearing products should be added. Radix et Rhizoma Rhei, Natrii Sulfas, and Fructus Aurantii Immaturus can be added for patients with excess heat, abdominal distension, constipation, and yellow and thick fur. Gaza Ginseng, Ophiopogon japonicus, Dendrobium nobile and Radix Rehmanniae are suitable for patients with phlegm-heat injury to body fluids, dry red tongue and yellow and rough fur.
Phlegm and blood stasis syndrome
In addition to the above symptoms of closed syndrome, there are white face and dark lips, restlessness, tepid limbs, excessive phlegm and saliva, white and greasy fur and heavy and slippery pulse.
The essence of syndrome mechanism: excessive phlegm, clearing the orifices with upper phlegm, inner Mongolia's mind and brain-machine occlusion.
Treatment: resolving phlegm and calming wind, relieving depression and inducing resuscitation;
Representative: Ditan Decoction. This prescription is used for resolving phlegm and inducing resuscitation, and for people with excessive phlegm and mental retardation. Can also be used as; Nine xiang xiang should be depressed to begin to understand:
Commonly used drugs: Pinellia ternata, Poria, Orange, Bamboo shavings for resolving phlegm; Radix Curcumae, Rhizoma Acori Graminei, and Bile Star resolve phlegm and begin to understand; Gastrodia elata, Uncaria rhynchophylla and Bombyx Batryticatus stop wind and resolve phlegm.
For those affected by wind, Rhizoma Gastrodiae and Ramulus Uncariae cum Uncis are added to calm the internal wind; Scutellariae Radix and Coptidis Rhizoma are added for patients with heat syndrome; Seeing that Dai Yang's syndrome is more serious, it should be treated with Shenfu decoction, Baitong plus pig bile decoction.
2. If the syndrome breaks, the yin will be exhausted and the yang will die.
Sudden fainting, unconsciousness, closed eyes, stuffy nose, snoring, cold hands and feet, sweating, white urine, limb paralysis, pale tongue, weak pulse or heartbroken.
The gist of the evidence: goodness is invincible, vitality is weak, and yin and yang are heartbroken.
Representative: Shenfu Decoction and Shengmai Powder. Shenfu decoction is used to replenish qi and restore yang, and it is used for yang deficiency, sweating and cold limbs; Shengmai powder is used for invigorating qi and nourishing yin, and is used for the failure of body fluid and qi. Both of them have the functions of invigorating qi and restoring yang, saving yin and strengthening the body, and are mainly used to treat the syndrome of yin exhaustion and yang decline. Shenmai injection or Shengmai injection can also be used for intravenous drip.
Commonly used drugs: ginseng and aconite root benefit qi and restore yang; Ophiopogon japonicus, Schisandra chinensis and Cornus officinalis nourish yin and astringe yang.
Yin doesn't love Yang, Yang floats outside, body fluid can't be hidden inside, keel is added when sweat is excessive, and oyster sweat returns to Yang; * * * For those with listlessness, dry tongue and weak pulse, Polygonatum odoratum and Polygonatum sibiricum should be added to nourish yin and protect body fluid.
convalescence
After the first aid in the acute phase of stroke, if the consciousness gradually wakes up, the phlegm-fire gradually subsides, the diet is slightly promoted, and the recovery period gradually enters, but the sequelae are hemiplegia. Mouth deviation, slurred speech or aphonia, etc. At this time, active treatment and intensive nursing are still needed.
Acupuncture and medication can improve the curative effect. According to the condition, drug treatment can treat both the symptoms and root causes, or adopt the method of standard before standard. Treating the symptoms should be searching for wind and resolving phlegm, dredging collaterals and removing blood stasis; Those with hyperactivity of liver yang should calm the liver and suppress Yang Can. It is advisable to tonify qi and blood, liver and kidney or yin and yang.
1, wind phlegm and blood stasis syndrome
Oblique mouth and eyes, astringent tongue or aphasia, hemiplegia, numbness of limbs, greasy fur, dark purple tongue and slippery pulse.
Summary of syndrome mechanism: wind and phlegm block collaterals, and qi and blood execution is unfavorable.
Treatment: searching for wind and resolving phlegm, removing blood stasis and dredging collaterals.
Representative: Jieyudan addition and subtraction. This recipe can dispel wind, eliminate phlegm and dredge collaterals, and treat wind and phlegm to block Lian Quan, with a strong and silent tongue.
Commonly used drugs: Gastrodia elata, Arisaema cum bile, concretio silicea bambusae, Pinellia ternata and dried tangerine peel; Pheretima, Bombyx Batryticatus and Scorpio search for wind and dredge collaterals; Cortex et Radix Polygalae, Rhizoma Acori Graminei, Herba Siegesbeckiae, Ramulus Mori, Caulis Spatholobi, Radix Salviae Miltiorrhizae and Flos Carthami.
For patients with excessive phlegm heat, Fructus Trichosanthis, Zhuru and Bulbus Fritillariae Cirrhosae are added to clear phlegm heat; Liver yang hyperactivity, dizziness and headache, red face and yellow fur, red tongue and strong pulse, and Uncaria, Concha Haliotidis and Prunella vulgaris are added to calm the liver and calm the wind and subdue the yang; Dry throat, add Trichosanthis Radix and Radix Asparagi to nourish yin and moisten dryness.
2. Qi deficiency and collateral stasis syndrome
Limbs are withered and useless, limbs are weak, complexion is sallow, tongue is pale purple or ecchymosis, fur is thin and white, and pulse is thin and astringent or thin.
Overview of syndrome mechanism: Qi deficiency and blood stasis, pulse obstruction and arthralgia syndrome.
Treatment: Yiqi Yangxue, Huayu Tongluo.
Representative: Buyang Huanwu Decoction. This recipe can replenish qi and nourish blood, remove blood stasis and dredge collaterals, and is suitable for stroke recovery, qi deficiency and blood stasis, without hemiplegia, mouth and eyes askew and poor language.
Commonly used drugs: Astragalus qi and blood; Peach kernel, safflower, red peony root, angelica, Ligusticum wallichii nourish blood and promote blood circulation, remove blood stasis and dredge collaterals; Lumbricus and Achyranthes bidentata lower blood to dredge collaterals.
Blood deficiency, add Lycium barbarum and Polygonum multiflorum to replenish blood; Cold limbs, loss of yang temperature, plus cassia twig to warm the meridians and dredge the pulse; The waist and knees are sore, and Radix Dipsaci, Herba Taxilli and Eucommiae Cortex are added to strengthen bones and muscles and strengthen the waist and knees.
3. Liver and kidney deficiency syndrome
Hemiplegia, stiff limbs, contracture and deformation, strong tongue without language, or hemiplegia, atrophy of limb muscles, thin red pulse, or deep red pulse.
Summary of syndrome mechanism: liver and kidney deficiency, yin and blood deficiency, tendon and vein dystrophy.
Treatment: nourishing liver and kidney.
Representative: Zuo Guiwan and Dihuang Yinzi. Zuogui Pill is specially used for nourishing the true yin of liver and kidney, and is used for the diseases of insufficient essence and blood, inability to nourish tendons, weakness of waist and knees, and weakness of limbs; Dihuang Yinzi has the effects of nourishing kidney yin, benefiting kidney yang, inducing resuscitation and resolving phlegm, and can be used for symptoms such as pale tongue, excessive phlegm and emaciation of feet.
Commonly used drugs: Radix Rehmanniae, Polygoni Multiflori Radix, Fructus Lycii and Corni Fructus; Ophiopogon japonicus and Dendrobium nobile nourish yin and promote fluid production; Angelica sinensis and Spatholobus suberectus nourish blood and dredge collaterals.
Addition and subtraction: if the waist is sore and the legs are soft, Eucommia ulmoides, Taxilli and Achyranthes bidentata are added to strengthen the waist; For kidney yang deficiency, Radix Morindae Officinalis, Herba Cistanches, Radix Aconiti Lateralis Preparata and Cortex Cinnamomi are added to warm and tonify kidney yang; For patients with turbid phlegm, Rhizoma Acori Graminei, Cortex et Radix Polygalae and Poria are added for resolving phlegm and inducing resuscitation.
Western medicine treatment
Western medicines for preventing and treating stroke include aspirin, biguanide chloride, cerebrolysin tablets, mecobalamin, etc., all of which are reliable and targeted. Among them, aspirin is the basic drug to prevent and treat stroke, which has a certain effect on preventing the recurrence of stroke. However, the clinical application of aspirin shows that 47% of patients have drug resistance, and even aspirin enteric-coated tablets will cause burden and influence on gastrointestinal tract. Patients with various bleeding tendencies should be forbidden to use aspirin and take it.