At present, congenital diseases have become the main cause of infant death. At present, there are more than 7000 different hereditary congenital diseases, and Down syndrome is one of the chromosome diseases with high incidence.
It is estimated that there are more than 600,000 patients with Down syndrome in China, resulting in an economic burden of about 2 billion.
Extended data:
Avoiding goiter before pregnancy can avoid this symptom.
"International face" is a genetic disease. According to reports, the probability of pregnant women under the age of 30 giving birth to children is11000; After the age of 35, it rises to 1/200, and this probability increases with the age of pregnant women.
What is a chromosomal disease? Experts made an image metaphor: We often compare chromosomes to a train. There are 46 carriages, and the substances loaded in the carriages are special substances called genes, and each carriage has about a thousand genes. Chromosomes can not only be abnormal in number, but also lead to structural distortion, and the resulting disease is chromosome disease.
Down syndrome is one of the most common chromosome diseases in human beings, also known as chromosome syndrome, because it often manifests as a syndrome with many malformations.
In addition to the visible "international face", patients with Down syndrome have serious mental retardation; 50% suffer from various congenital heart diseases; Male patients are infertile, female patients are infertile occasionally, 1/2 children will get sick; The risk of leukemia in children is 10-20 times that of normal people. Often hearing loss, life can not take care of themselves.
References:
International Face-Baidu Encyclopedia